US TSCA Inventory

Section 8 (b) of the Toxic Substances Control Act (TSCA) requires EPA to compile, keep current, and publish a list of each chemical substance that is manufactured or processed in the United States. Since EPA published the final TSCA Inventory Reporting Rule on December 23, 1977, the TSCA Inventory has grown to include the identities of over 83,000 chemical substances.

Non-confidential portion of the TSCA Inventory can be downloaded here


If an intended manufacturer or importer of a chemical substance is unsure of the TSCA Inventory status of the chemical (e.g., cannot find that substance on one of the public sources of non-confidential TSCA Inventory data), the company or representative can obtain a written determination from EPA if it can demonstrate a “genuine intent.” It can do this by submitting a Bona Fide Intent to Manufacture or Import Notice pursuant to the procedures at 40 CFR section 720.25.


Substances not on the TSCA Inventory are considered "new" chemicals and shall be notified to EPA through Premanufacture Notice (PMN). However, there are exemptions for PMN.

  • Testing Marketing: Manufacturers are permitted to assess the commercial viability of a new chemical and to receive customer feedback before filing a PMN.Use of this exemption requires submission of an application for Test Marketing Exemption to EPA
  • Low Volume: Manufacturers can produce low volumes (up to 10,000 kg) of certain new chemical substances without full PMN review under the Low Volume Exemption (LVE). Use of this exemption requires submission of Form 7710-25 (the standard PMN form) to EPA.
  • Low Release / Low Exposure: EPA provides the LoREX exemption for chemical substances with low environmental releases and human exposure. Prior approval is required.
  • R&D, polymer and export only: Prior approval is not required.

About CIRS

We have provided one-stop chemical inventory search services for many companies doing business in Asia (for example, China, Japan, Korea, Malaysia, and Philippine). We help them find out whether their chemicals are regulated in those countries or regions and offer free initial consultations about how to comply. We also prepare or translate GHS compliant SDS and label in accordance with their national chemical legislation at affordable prices.

If you have any questions about chemical compliance in the Asia-pacific region, please contact:

  • CIRS Europe
    Unit 1 Ardee Business Park, Hale Street, Ardee, Co. Louth, Ireland
    Tel : +353 41 9806 916 | Fax : +353 41 9806 999
    Email: service@cirs-reach.com
  • Mr. Eric Xiong, China Office
    11F Building 1, Dongguan Hi-Tech Park, 1288 Chunbo Road, Binjiang District, Hangzhou 310052, China
    Tel: +86-571 8720 89716579 | Fax: +86-571 8720 6533
    Email: Eric.Xiong@cirs-reach.com